Nise 100 Tablet is used to treat pain and dysmenorrhea (painful periods or menstrual cramps). Besides this, it is also used to treat dental pain that can result from damage to the tooth nerve, infection, decay, extraction, or injury. It contains Nimesulide, which works by blocking the effects of a chemical called prostaglandin, which is responsible for inducing pain and inflammation in the body. It may cause common side effects like nausea, diarrhoea, changes in liver enzymes, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.